Phase I Clinical Trial – Pharmacokinetics

350% Higher Bioavailability*

  • 30% higher total bioavailability over 24 hours compared to an oromucosal spray
  • At peak levels Satipharm CBD Gelpell® capsules have a 70% higher concentration in the body (Mean Maximum Concentration) compared to an oromucosal spray
  • This extrapolates to 350%+ higher bioavailability when compared to a standard CBD oil taken orally

*Bioavailability - Is the proportion of a consumed substance, which enters the bloodstream unaltered, so can have an active effect on the body. A substance (such as CBD oil) may be readily absorbed but suffer significant metabolism by the liver before reaching the blood stream, thereby reducing its bioavailability.

 

    PLASMA CONCENTRATION-OVER-TIME Graph
    Plasma concentration-over-time curves for CBD from a single dose of Satipharm Gelpell (containing 10 mg CBD) and oromucosal spray (at a total dose of 10 mg CBD). n = 14

    Higher Stability

    We have over two years of stability data proving that the Gelpell® three dimensional natural gelatine matrix stabilises the CBD, inhibiting degradation.

    CBD DEGRADATION RATES